If you have severe
rheumatoid arthritis,
psoriasis, or cancer, your healthcare provider may recommend a drug called methotrexate (
Rheumatrex®,
Trexall®). This powerful medicine comes in the form of a tablet or an injection. It works by inhibiting a cell's ability to repair and replicate (copy) itself. It's not entirely clear how the medication works to treat rheumatoid
arthritis, although it may work by affecting the immune system.
Because this product kills both cancer cells and healthy cells, side effects can be significant. According to the drug's prescribing information, the most
common methotrexate side effects include high liver enzymes, excessive fatigue, and low white blood cell counts, among others. Prior to starting treatment, tell your healthcare provider if you are taking any other medications (including prescription and nonprescription products) or have any other medical conditions. Also, let him or her know if you are pregnant, thinking of becoming pregnant, or breastfeeding.
(For more information on this drug, click Methotrexate. This article offers details on safety issues to be aware of, other side effects, dosing guidelines, and more.)
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