Psoriasis Home > Topicort Drug Interactions

If you are taking aldesleukin or corticorelin, be sure to let your healthcare provider know before starting treatment with Topicort. Combining these drugs with Topicort can lead to negative interactions, possibly decreasing the effectiveness of the medications. To avoid any other complications, make sure your healthcare provider is aware of all medications and supplements you are currently taking.

An Overview of Interactions With Topicort

Topicort® (desoximetasone) is generally unlikely to react with other medications. However, there are a few potential drug interactions that may occur. Some of the drugs that can lead to interactions with Topicort include but are not limited to:

Topicort Drug Interactions Explained

The following sections explain in detail the potentially negative reactions that can occur when Topicort is combined with any of the drugs listed above.
Corticosteroids, including Topicort, can make aldesleukin (a chemotherapy medication) less effective. In general, these medications should not be used together.
Corticosteroids, including Topicort, can make corticorelin less effective. Corticorelin is used as a diagnostic agent in tests for Cushing's syndrome or other similar problems. If you are being tested for Cushing's disease, make sure your healthcare provider knows you have been using Topicort.

Final Thoughts

It is possible that not all drug interactions with Topicort were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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