Psoriasis Home > Drug Interactions With Fluocinonide Ointment

When certain medicines are combined with fluocinonide ointment, drug interactions could occur. For instance, fluocinonide ointment can make medications like corticorelin or aldesleukin less effective. It is important that your healthcare provider knows if you are taking either of these medications before using the ointment. He or she may recommend you not use these medications together.

An Overview of Fluocinonide Ointment Interactions

Fluocinonide ointment (Lidex®) is generally unlikely to react with other medications. However, there are a few potential drug interactions that may occur. Some of the drugs that can lead to interactions with fluocinonide ointment include but are not limited to:

Drug Interactions With Fluocinonide Ointment Explained

The following sections explain in detail the potentially negative reactions that can occur when fluocinonide ointment is combined with any of the drugs listed above.
Corticosteroids, including fluocinonide ointment, can make aldesleukin (a chemotherapy medication) less effective. In general, these medications should not be used together.
Corticosteroids, including fluocinonide ointment, can make corticorelin less effective. Corticorelin is used as a diagnostic agent in tests for Cushing's syndrome or other similar problems. If you are being tested for Cushing's disease, make sure your healthcare provider knows you have been using fluocinonide ointment.

Final Thoughts

It is possible that not all fluocinonide ointment interactions were discussed in this article. Therefore, you should talk with your pharmacist or healthcare provider about the specific drug interactions that may apply to you.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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