Psoriasis Home > Derma-Smoothe Drug Interactions

Although Derma-Smoothe is generally unlikely to interact with other medications, there are a few drugs that should not be used with this skin oil. For example, make sure your healthcare provider knows you are using Derma-Smoothe before taking aldesleukin, corticorelin, or deferasirox. Drug interactions such as these may decrease the effectiveness of the medications or increase your risk for side effects.

An Overview of Interactions With Derma-Smoothe

Derma-Smoothe/FS® (fluocinolone oil) is generally unlikely to react with most other medications. Some of the medications that may lead to a drug interaction with Derma-Smoothe include:

Derma-Smoothe Drug Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when Derma-Smoothe is combined with any of the drugs listed above.
Corticosteroids, such as Derma-Smoothe, can make aldesleukin less effective. In general, these medicines should not be used together.
Corticorelin is used as a test to help healthcare providers differentiate between types of Cushing's syndrome, or similar conditions. Derma-Smoothe may interfere with corticorelin test results. Make sure your healthcare provider knows you have been using Derma-Smoothe if you are receiving a corticorelin test.
Derma-Smoothe may increase the risk for certain deferasirox side effects, in particular the risk for stomach or intestinal bleeding. This interaction is only expected to be a potential problem in cases where significant amounts of Derma-Smoothe were absorbed through the skin into the body and caused side effects, which could happen with long-term Derma-Smoothe use.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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