Psoriasis Home > Amevive Side Effects

In clinical studies, up to 6 percent of people taking Amevive experienced chills. However, this reaction occurred mostly when the drug was given by IV, not injected into a muscle, which is the recommended delivery method. Other common side effects included dizziness, nausea, and cough. If you develop any side effects while taking Amevive, or if something "just doesn't seem right," tell your healthcare provider.

An Introduction to Amevive Side Effects

As with any medicine, side effects are possible with Amevive® (alefacept). However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Amevive. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Amevive

Amevive has been studied thoroughly in clinical trials. In these studies, the side effects that occur in a group of people given the drug are documented and compared to those that occur in a similar group of people given a placebo (in this case, an injection with no active ingredient). This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group given the placebo.
In these studies, the most common Amevive side effect was chills, which occurred in up to 6 percent of people. Keep in mind, however, that chills occurred predominantly when this medication was given by IV instead of by injection into a muscle, as is currently recommended.
Other common side effects (occurring in 2 to 5 percent of people) included:
  • Sore throat
  • Dizziness
  • Cough
  • Nausea
  • Itching
  • Muscle pain
  • Pain at the injection site
  • Inflammation at the injection site
  • Accidental injury.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
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