Psoriasis Home > Amevive and Pregnancy

In studies that looked at the effects of Amevive (alefacept) on pregnant monkeys, no problems were seen in the offspring when up to 62 times the recommended equivalent human dosage was given. Because of these results, the FDA considers this product a pregnancy Category B drug, which means that it is generally considered safe for women who are expecting.

I'm Pregnant -- Can I Take Amevive?

Amevive® (alefacept) is a prescription medication approved to treat psoriasis. Although this medication has not been studied in pregnant women, based on the results of animal studies, Amevive appears to be safe for use during pregnancy. Keep in mind, however, that the full risks are currently unknown.

What Is Pregnancy Category B?

The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category B is given to medicines that have not been adequately studied in pregnant humans but do not appear to cause harm to the fetus in animal studies.
Studies have shown that giving even very large doses of Amevive (up to 62 times the recommended equivalent dosage in humans) to pregnant monkeys did not cause any problems for the offspring.
However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category B medicine should be given to a pregnant woman only if the healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.

Final Thoughts on Amevive and Pregnancy

If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. Your healthcare provider will consider both the benefits and risks of using Amevive during pregnancy before making a recommendation in your particular situation.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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