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Locoid Side Effects
When steroids, such as Locoid, were studied in clinical trials, the most commonly reported side effects included burning, itching, and skin irritation. In most cases, reactions are generally minor and require little treatment. However, you should seek medical attention right away if you are using Locoid and develop reactions that are potentially serious, such as severe fluid retention, infections, or an unexplained rash.
Just like any medicine, Locoid® (hydrocortisone butyrate) can cause side effects. However, not everyone who uses the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider.
(This article covers many, but not all, of the possible side effects with Locoid. Your healthcare provider can discuss a more complete list with you.)
As is common with older medications, there is only vague side effect information available for Locoid. In fact, the side effects listed in the prescribing information are not specific to Locoid, but are side effects that are common with all topical steroids.
Common side effects of steroids, such as Locoid, include (in order from most common to least common):
- Burning
- Itching
- Irritation
- Drying
- Inflammation or infection of skin follicles (folliculitis)
- Increased sweating
- Acne
- Decreased skin pigmentation
- Rash around the mouth
- Allergic contact dermatitis (allergic skin reactions)
- Soft, whitened skin (much like skin that is constantly wet)
- Weakening and thinning of the skin
- Stretch marks
- Heat rash.
For all forms of Locoid, side effects are more likely to occur when a dressing, such as a bandage, is used to cover the medication. Do not use a dressing or bandage unless your healthcare provider specifically tells you to do so.
Written by/reviewed by: Kristi Monson, PharmD
Last reviewed by: Kristi Monson, PharmD



