Drug Interactions With Golimumab

"Live" vaccinations (such as chickenpox vaccine or polio vaccine) can interact with golimumab. In addition, several other drugs can interfere with golimumab, including cyclosporine, theophylline, and anakinra. These interactions can increase your risk of infections and other problems. If such problems are a concern, your healthcare provider may decide to monitor you more closely.

Golimumab Drug Information

An Overview of Golimumab Interactions

Golimumab (Simponi™) can potentially interact with a few other medications. Some of the drugs that may lead to interactions with golimumab include:

Abatacept (Orencia^®)
Anakinra (Kineret^®)
Cyclosporine (Gengraf^®, Neoral^®, Sandimmune^®)
"Live" vaccinations, including:

Chickenpox vaccine (varicella vaccine)
FluMist^® (the nasal vaccine for influenza; the injected vaccine is not live)
MMR vaccine (measles, mumps, and rubella vaccine)
Polio vaccine
Rotavirus vaccine
Smallpox vaccine
Yellow fever vaccine
BCG vaccine (used in some countries for tuberculosis)

Theophylline (Uniphyl^®, Theocron^®, TheoCap^®, Theo-24^®, Elixophyllin^®)
Warfarin (Coumadin^®, Jantoven^®).

More Details on Golimumab Drug Interactions

The following sections explain in detail the potentially negative interactions that can occur when golimumab is combined with any of the drugs listed above.

Abatacept

Taking golimumab with abatacept can increase your risk of getting an infection. In general, these two medications should not be combined.

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