Side Effects of Etanercept

Common Side Effects of Etanercept

Etanercept has been studied thoroughly in clinical trials, with many people having been evaluated. In these studies, the side effects occurring in a group of people taking the drug were documented and compared to the side effects that occurred in a similar group of people not taking the medicine. As a result, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine.
Based on these studies, the most common side effects of etanercept include:
  • Injection site reactions (redness, rash, swelling, itching, or bruising) -- occurring in up to 37 percent of people
  • Infections such as the common cold or a sinus infection -- up to 35 percent
  • Headaches -- up to 17 percent
  • Irritated or runny nose -- up to 12 percent
  • Dizziness -- up to 7 percent
  • Sore throat -- up to 7 percent
  • Cough -- up to 6 percent
  • General weakness -- up to 5 percent
  • Abdominal pain (stomach pain) -- up to 5 percent
  • Breathing problems -- up to 5 percent
  • Heartburn -- up to 4 percent
  • Vomiting -- up to 3 percent
  • Mouth ulcers (canker sores) -- up to 2 percent.

Rare Etanercept Side Effects

Rare side effects of etanercept occur in less than 1 percent of people taking the medication. Because these side effects are so uncommon, it is difficult to tell whether they are caused by etanercept or something else.
Some of these possible side effects include but are not limited to:
  • Serious infections, including:


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Etanercept (Enbrel)

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