Drug Interactions With Etanercept

"Live" vaccinations, anakinra, and cyclophosphamide can all cause etanercept drug interactions, which can cause the body to metabolize the medications differently than intended and may lead to problems. Some of these interactions can increase your risk of infections or certain tumors. Therefore, talk to your healthcare provider about any possible drug interactions that may apply to you.

Etanercept (Enbrel)

An Overview of Etanercept Interactions

Etanercept (Enbrel^®) can potentially interact with many drugs. Some of the drugs that may lead to etanercept drug interactions include:

"Live" vaccinations, including:

Chickenpox vaccine (varicella vaccine)
FluMist^® (the nasal vaccine for influenza; the injected vaccine is not live)
MMR (measles, mumps, rubella) vaccine
Polio vaccine
Rotavirus vaccine
Smallpox vaccine
Yellow fever vaccine
BCG vaccine (used in some countries for tuberculosis)

More Information on Drug Interactions With Etanercept

The following sections explain in detail the potentially negative interactions that can occur if etanercept is combined with any of the drugs listed above.

Live Vaccines

Live vaccines are immunizations that contain live viruses or bacteria. If you receive a live vaccine while taking etanercept, you might become infected with the virus or bacteria from the vaccine. Also, etanercept can make live vaccines less effective. You should not receive live vaccinations while taking this drug.

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