Drug Interactions With Cyclosporine

Tacrolimus
Taking cyclosporine with tacrolimus may increase your risk for potentially serious cyclosporine side effects, including infections and skin cancer. Although the risk for these serious side effects is rare, it is generally recommended that tacrolimus not be used with medicines that weaken the immune system, including cyclosporine.
 
Tolvaptan
Cyclosporine may increase the amount of tolvaptan in your blood, potentially increasing your risk for side effects. It is generally recommended that these medicines not be taken together.
 
Topotecan
Cyclosporine may increase the amount of topotecan in your blood, potentially increasing your risk for side effects. This interaction is expected to be more significant for oral topotecan, compared with the intravenous (IV) form. It is generally recommended that these medicines not be taken together.
 

Final Thoughts

Because cyclosporine can interact with so many different medicines, it is not possible to discuss them all in this article. Therefore, you should talk with your pharmacist or healthcare provider about specific interactions that may apply to you. Always double-check with your healthcare provider and your pharmacist before starting or stopping any medication while you are taking cyclosporine, due to the high risk for serious drug interactions.
 
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Cyclosporine Drug Information

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