Cyclocort and Pregnancy

When Cyclocort (amcinonide) was given to pregnant animals, it increased the risk for birth defects, poor fetal growth, and decreased survival. Although this risk may be lower when using topical steroids like Cyclocort, it is generally recommended that women use the lowest effective dose for the shortest time possible during pregnancy.

Can Pregnant Women Use Cyclocort?

Cyclocort® (amcinonide) is a prescription topical steroid approved for treating itching and inflammation due to a wide variety of skin conditions. Based on information currently available, it is unclear if the drug is safe for use during pregnancy. As with most steroids, it should be used only if necessary, at the lowest effective dose, and for the shortest possible time during pregnancy.
 

What Is Pregnancy Category C?

Cyclocort is classified as a pregnancy Category C drug. The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is used during pregnancy. Pregnancy Category C is given to medicines that have not been adequately studied in pregnant humans but have caused fetal harm in animal studies.
 
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
 
Animal studies have shown that steroids, including Cyclocort, may increase the risk for birth defects, such as cleft palate, and may cause other problems, such as poor fetal growth or decreased survival. Similar problems might also occur in humans, although the risk is probably smaller for topical steroids that are applied to the skin, like Cyclocort.
 
While short-term use (a few days) of this drug applied to a small area of the body is probably not likely to cause problems, extended use or use over a large area of the body should probably be avoided during pregnancy, if possible.
 
Pregnancy and Pain

Cyclocort Medication Information

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