Cordran Tape and Pregnancy
When steroids such as Cordran Tape (flurandrenolide tape) were studied in pregnant animals, there was an increased risk for problems such as birth defects and reduced survival rates. It is unknown if these problems would also occur in humans, but it is probably best to avoid using this medicine over a large area for extended periods when pregnant.
Can Pregnant Women Use Cordran Tape?Cordran® Tape (flurandrenolide tape) is a prescription topical steroid approved for treating a variety of skin conditions. As is common with many medications, it is unclear if the drug is safe for use during pregnancy. In general, steroids should be used only if necessary, at the lowest effective dose, and for the shortest time possible during pregnancy.
Because Cordran Tape is a highly potent steroid, it might be wise for a pregnant woman to try a less potent steroid first.
What Is Pregnancy Category C?The U.S. Food and Drug Administration (FDA) uses a category system to classify the possible risks to a fetus when a specific medicine is taken during pregnancy. Pregnancy Category C is given to medicines that have not been studied in pregnant humans but do appear to cause harm to the fetus in animal studies.
In addition, medicines that have not been studied in any pregnant women or animals are automatically given a pregnancy Category C rating.
Cordran Tape is a steroid. Animal studies have shown that steroids may increase the risk of birth defects, such as cleft palate, and may cause other problems, such as poor fetal growth or decreased survival.
Animal studies have also shown that flurandrenolide (the active ingredient in Cordran Tape) appeared to increase the risk of poor fetal growth, miscarriages, and fetal malformations. Similar problems might also occur in humans, although the risk is probably smaller with topical steroids that are applied to the skin, like Cordran Tape.
While short-term use (a few days) of Cordran Tape applied to a small area of the body is probably not likely to cause problems (although this is not known for sure), extended use or use over a large area of the body should be avoided during pregnancy, if possible. In some cases, the benefits to the mother might outweigh the possible risks to the fetus.